ISSN 2394-5125
 

Research Article 


COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova.

Abstract
The aim of our work was to conduct a comparative analysis of the IL-8 cytokine polymorphism in inflammatory of children bronchial diseases of the Uzbek population. To achieve this goal, 138 cases of the diseases were analyzed, of which 1st group consisted of children with acute obstructive bronchitis (AOB), 2nd group with recurrent obstructive bronchitis (RBО), and 3rd group patients with bronchial asthma (BA) of age from 6 months up to 10 years. A comparative analysis of IL-8 and total IgE in AOB, RBO and BA showed a significant increase in IL-8 and an increase in IgE level in RBO and BA compared with the group of AOB and healthy children. The obtained clinical-anamnestic and immunological results of the study allow the prediction of RBO and BA in children with AOB. A significant increase in IL-8 in combination with high IgE is an unfavorable prognostic criterion for the formation of RBO and BA in children.

Key words: children, bronchitis, bronchial asthma, cytokine, obstruction


 
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How to Cite this Article
Pubmed Style

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova. COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION. JCR. 2020; 7(17): 2292-2297. doi:10.31838/jcr.07.17.282


Web Style

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova. COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION. http://www.jcreview.com/?mno=96026 [Access: August 17, 2021]. doi:10.31838/jcr.07.17.282


AMA (American Medical Association) Style

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova. COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION. JCR. 2020; 7(17): 2292-2297. doi:10.31838/jcr.07.17.282



Vancouver/ICMJE Style

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova. COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION. JCR. (2020), [cited August 17, 2021]; 7(17): 2292-2297. doi:10.31838/jcr.07.17.282



Harvard Style

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova (2020) COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION. JCR, 7 (17), 2292-2297. doi:10.31838/jcr.07.17.282



Turabian Style

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova. 2020. COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION. Journal of Critical Reviews, 7 (17), 2292-2297. doi:10.31838/jcr.07.17.282



Chicago Style

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova. "COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION." Journal of Critical Reviews 7 (2020), 2292-2297. doi:10.31838/jcr.07.17.282



MLA (The Modern Language Association) Style

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova. "COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION." Journal of Critical Reviews 7.17 (2020), 2292-2297. Print. doi:10.31838/jcr.07.17.282



APA (American Psychological Association) Style

Umida I. Zakirova, Ilkhomjon A. Karimdjanov, G.H Iskanova, G.A. Yusupova, N.A. Israilova, N.B. Sadikova (2020) COMPARATIVE ANALYSIS OF IL-8 CYTOKINE POLYMORPHISM IN INFLAMMATORY DISEASES OF THE BRONCHI IN CHILDREN OF THE UZBEK POPULATION. Journal of Critical Reviews, 7 (17), 2292-2297. doi:10.31838/jcr.07.17.282