ISSN 2394-5125
 

Review Article 


PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva.

Abstract
Background: Almost all pesticides have hepatotoxic effects even at low doses, making liver protection from pesticide toxic effects one of the urgent regional medical and social problems
Objective: The purpose of this work was to assess the functional state of the liver of animals poisoned with the pesticide Bagira, using in their diet dishes made from local food and additional introduction of a complex of local herbal medicines into the diet.
Methods: The experiments were carried out on 147 white male rats weighing 170-190 g. Bagira" pesticide in dose 1/20 Lethal dose 50 (LD50)-44.3 mg/kg (LD50=886 mg/kg) was injected daily intragastricly.
Results (Findings): The results of experimental studies are presented, which show that the use in the experiment of feed prepared from local products together with decoction of medicinal plants, allows to achieve a sharp improvement in biochemical indicators of the functional state of the liver of rats with chronic liver damage by the pesticide "Bagira", compared with indicators of animals on the diet of vivarium. The data on increase of liver function and positive influence of new diets on liver excretion function of animals have been received.
Conclusions: 1. The results of the experiments show that the use in the experiment of feed prepared from local products together with decoction of medicinal plants, allows to achieve a sharp improvement in biochemical indicators of the functional state of the liver compared with the indicators of animals on the diet of vivarium.
2. An increase in the amount of protein in liver tissue, a decrease in the activity of Alanine Transferase (ALT) and Aspartate Transferase (AST) with the use of local products indicates an increase in liver function, and a decrease in bilirubin content indicates their positive impact on liver excretion function.

Key words: local, food, medicinal plants, pesticide


 
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How to Cite this Article
Pubmed Style

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva. PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING. JCR. 2020; 7(2): 736-737. doi:10.31838/jcr.07.02.135


Web Style

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva. PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING. http://www.jcreview.com/?mno=90065 [Access: June 02, 2021]. doi:10.31838/jcr.07.02.135


AMA (American Medical Association) Style

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva. PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING. JCR. 2020; 7(2): 736-737. doi:10.31838/jcr.07.02.135



Vancouver/ICMJE Style

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva. PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING. JCR. (2020), [cited June 02, 2021]; 7(2): 736-737. doi:10.31838/jcr.07.02.135



Harvard Style

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva (2020) PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING. JCR, 7 (2), 736-737. doi:10.31838/jcr.07.02.135



Turabian Style

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva. 2020. PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING. Journal of Critical Reviews, 7 (2), 736-737. doi:10.31838/jcr.07.02.135



Chicago Style

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva. "PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING." Journal of Critical Reviews 7 (2020), 736-737. doi:10.31838/jcr.07.02.135



MLA (The Modern Language Association) Style

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva. "PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING." Journal of Critical Reviews 7.2 (2020), 736-737. Print. doi:10.31838/jcr.07.02.135



APA (American Psychological Association) Style

Mukaddaskhon Khamrakulova,Askar Sadikov,Ernazar Navruzov,Munisa Ilyasova,Nargiza Ergasheva (2020) PILOT RATIONALE FOR THE USE OF LOCAL FOOD AND MEDICINAL PLANTS TO REGULATE LIVER FUNCTION IN CASES OF PESTICIDE POISONING. Journal of Critical Reviews, 7 (2), 736-737. doi:10.31838/jcr.07.02.135