ISSN 2394-5125
 

Research Article 


ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT

Mitral valve replacement; Cold cardioplegia; warm cardioplegia.

Abstract
Background: The cardioplegic arrest is essential for motionless and bloodless heart valve
surgery. The objective of this work was to compare antegrade cold versus warm blood cardioplegia during
valve surgery
Methods:This randomized controlled study included 100 patients who had mitral valve surgery. Patients
were randomly assigned into two groups; the cold cardioplegic group (n= 50) and the warm cardioplegic
group (n= 50)
Results: There was no significant difference in age and sex pre-operative LVEF between groups (p= 0.53
and 0.34;0.42 respectively). Cross clamp time was significantly longer in warm group (35.70 3.64 vs.
30.67 4.84 (minute); P< 0.001) ;however Both groups had insignificant differences as regard total bypass
time (p=0.29).median number of DC shock was significantly higher in cold group ( P< 0.001) joules of
DC shock was significantly higher in cold group (18.60 9.69 vs. 13 10.73 (joules); P< 0.001). while
number of cardioplegia dose is significantly higher in patients underwent warm cardioplegia (P< 0.001).
time for extubation longer in cold group (6.72 2.68 hours vs 5.26 1.91 hours; P< 0.001) . Dose of
inotropes was significantly higher in cold cardioplegia (0.06 0.03 vs. 0.05 0.02 (mic/kg/min).
post-operativecreatine kinase was significantly higher in cold group (629.22 159.76 vs 478.40 134.26
(u/l).post-operative creatine kinase-myocardial band (125.20 31.70 vs 111.04 35.97 (u/l).P< 0.001.postoperative
troponin is significantly higher among cold group (0.69 0.17 vs. 0.53 0.22 (ng/ml); P<
0.001).
Conclusion: Antegrade warm blood cardioplegia may provide better myocardial protection during valve
surgery compared to the cold cardioplegia. A larger study is recommended

Key words: Mitral valve replacement; Cold cardioplegia; warm cardioplegia


 
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Pubmed Style

replacement Mv, cardioplegia C, cardioplegia w. ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT. JCR. 2020; 7(10): 3086-3094. doi:10.31838/jcr.07.10.503


Web Style

replacement Mv, cardioplegia C, cardioplegia w. ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT. http://www.jcreview.com/?mno=129171 [Access: August 18, 2021]. doi:10.31838/jcr.07.10.503


AMA (American Medical Association) Style

replacement Mv, cardioplegia C, cardioplegia w. ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT. JCR. 2020; 7(10): 3086-3094. doi:10.31838/jcr.07.10.503



Vancouver/ICMJE Style

replacement Mv, cardioplegia C, cardioplegia w. ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT. JCR. (2020), [cited August 18, 2021]; 7(10): 3086-3094. doi:10.31838/jcr.07.10.503



Harvard Style

replacement, M. v., cardioplegia, . C. & cardioplegia, . w. (2020) ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT. JCR, 7 (10), 3086-3094. doi:10.31838/jcr.07.10.503



Turabian Style

replacement, Mitral valve, Cold cardioplegia, and warm cardioplegia. 2020. ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT. Journal of Critical Reviews, 7 (10), 3086-3094. doi:10.31838/jcr.07.10.503



Chicago Style

replacement, Mitral valve, Cold cardioplegia, and warm cardioplegia. "ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT." Journal of Critical Reviews 7 (2020), 3086-3094. doi:10.31838/jcr.07.10.503



MLA (The Modern Language Association) Style

replacement, Mitral valve, Cold cardioplegia, and warm cardioplegia. "ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT." Journal of Critical Reviews 7.10 (2020), 3086-3094. Print. doi:10.31838/jcr.07.10.503



APA (American Psychological Association) Style

replacement, M. v., cardioplegia, . C. & cardioplegia, . w. (2020) ANTEGRADE INTERMITTENT COLD CARDIOPLEGIA IN COMPARISON TO ANTEGRADE INTERMITTENT WARM CARDIOPLEGIA IN MITRAL VALVE REPLACEMENT. Journal of Critical Reviews, 7 (10), 3086-3094. doi:10.31838/jcr.07.10.503