ISSN 2394-5125
 

Research Article 


A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.

Harshitha C, Sayani Bhattacharyya.

Abstract
The decade advancement in the pharmaceutical industry has taken a new direction in the emerging field of nanoscience and nanotechnology. The potency of this technology is established in the multidisciplinary field of research area. It serves as a robust platform in the field of medical and pharmaceutical sciences to overcome the drawbacks of conventional drug delivery systems and in improving the bioavailability of a number of drugs. The progress in technology has been given a great deal of attention as it is associated with several drawbacks. The immediate challenge comes with its materials and properties at the nanoscale. It shows potential risk in drug penetration to the skin, gastrointestinal, respiratory and blood brain barrier which leads to death due to oxidative stress, cytotoxicity and genotoxicity. The risk extends to environmental concerns and public health. Therefore, the design and fabrication of nanoscience is an important consideration. The independent characterization, evaluation and assessment of performance for the nanoparticles need a better understanding in assessing stability, pharmacokinetics, biodistribution and toxicity of nanoformulations. The harmonization of concepts is thereby essential for smooth translation and regulatory decisions. This review includes the study of potential risk factors associated with the nanomaterials, and also includes the comparative study of FDA, Japan and European guidelines associated with the production of nanoparticles.

Key words: Nanotechnology, challenges, safety, regulatory view.


 
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How to Cite this Article
Pubmed Style

Harshitha C, Sayani Bhattacharyya. A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.. JCR. 2020; 7(9): 963-968. doi:10.31838/jcr.07.09.178


Web Style

Harshitha C, Sayani Bhattacharyya. A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.. http://www.jcreview.com/?mno=112616 [Access: May 30, 2021]. doi:10.31838/jcr.07.09.178


AMA (American Medical Association) Style

Harshitha C, Sayani Bhattacharyya. A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.. JCR. 2020; 7(9): 963-968. doi:10.31838/jcr.07.09.178



Vancouver/ICMJE Style

Harshitha C, Sayani Bhattacharyya. A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.. JCR. (2020), [cited May 30, 2021]; 7(9): 963-968. doi:10.31838/jcr.07.09.178



Harvard Style

Harshitha C, Sayani Bhattacharyya (2020) A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.. JCR, 7 (9), 963-968. doi:10.31838/jcr.07.09.178



Turabian Style

Harshitha C, Sayani Bhattacharyya. 2020. A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.. Journal of Critical Reviews, 7 (9), 963-968. doi:10.31838/jcr.07.09.178



Chicago Style

Harshitha C, Sayani Bhattacharyya. "A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.." Journal of Critical Reviews 7 (2020), 963-968. doi:10.31838/jcr.07.09.178



MLA (The Modern Language Association) Style

Harshitha C, Sayani Bhattacharyya. "A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.." Journal of Critical Reviews 7.9 (2020), 963-968. Print. doi:10.31838/jcr.07.09.178



APA (American Psychological Association) Style

Harshitha C, Sayani Bhattacharyya (2020) A BRIEF REVIEW ON NANOTECHNOLOGY AS A CHALLENGING FIELD IN PHARMACEUTICALS AND THEIR REGULATORY APPROVAL.. Journal of Critical Reviews, 7 (9), 963-968. doi:10.31838/jcr.07.09.178