Abstract

The present study provides a scientific evaluation for the wound healing potential of ethanolic (PJOH) extract of Prosopis JuliforaLinn. (PJ) plant. Materials and Methods: Excision, incision wounds were inflicted upon four groups of six rats each. Group I was assigned as control (ointment base). Group II was treated with 0.5% EtOH extract ointment. Group III was treated with 2% EtOH extract ointment, Group IV was treated with standard cream. The parameters observed were percentage of wound contraction, epithelialization period, tensile strength studies. Result: It was noted that the effect produced by the ethanolic extract of PJ ointment showed significant (P < 0.01) healing in all wound models when compared with the control group. All parameters such as wound contraction, epithelialization period, tensile strength showed significant (P < 0.01) changes when compared with the control. Conclusion: The ethanolic extract ointment of PJ effectively stimulates wound contraction; increases tensile strength of excision, incision wounds.

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