ISSN 2394-5125
 

Review Article 
JCR. 2016; 3(2): 48-54


A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT

HETAL PATEL, MUKESH GOHEL.

Abstract
The demand for directly compressible co-processed excipients has increased mainly due to the availability of high-speed tableting machines, time-saving in filing abbreviated new drug applications (ANDA), simplified validation and stability of active pharmaceutical ingredient (API). The cost of new excipient development is very high as it demands toxicity study also. Hence, industry has focused on co-processing of approved materials. The main aim of co-processing is to obtain a product with added value related to the ratio of its functionality/price. The risk to product quality is reduced, and productivity is improved due to the use of multifunctional co-processed excipients. In the present era, the Quality by Design (QbD) concept is useful for the development of multifunctional co-processed excipients. Co-processing is not restricted to diluents. It can be extended to other ingredients such as binders and disintegrants of tablets and capsules. There is also scope for obtaining patents by working upon newer avenues of developing multifunctional co-processed excipient for lozenges (e. g. iso-melt of sugar) or for herbal excipients. The present review focuses on formulation and evaluation techniques of multifunctional co-processed excipients. The characteristics of currently available multifunctional co-processed materials are enlisted in the review to facilitate further research by research scholars and R & D scientists.

Key words: Co-processed, Excipients, Oral drug delivery


 
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Pubmed Style

HETAL PATEL, MUKESH GOHEL. A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT. JCR. 2016; 3(2): 48-54.


Web Style

HETAL PATEL, MUKESH GOHEL. A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT. http://www.jcreview.com/?mno=302644771 [Access: May 31, 2021].


AMA (American Medical Association) Style

HETAL PATEL, MUKESH GOHEL. A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT. JCR. 2016; 3(2): 48-54.



Vancouver/ICMJE Style

HETAL PATEL, MUKESH GOHEL. A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT. JCR. (2016), [cited May 31, 2021]; 3(2): 48-54.



Harvard Style

HETAL PATEL, MUKESH GOHEL (2016) A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT. JCR, 3 (2), 48-54.



Turabian Style

HETAL PATEL, MUKESH GOHEL. 2016. A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT. Journal of Critical Reviews, 3 (2), 48-54.



Chicago Style

HETAL PATEL, MUKESH GOHEL. "A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT." Journal of Critical Reviews 3 (2016), 48-54.



MLA (The Modern Language Association) Style

HETAL PATEL, MUKESH GOHEL. "A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT." Journal of Critical Reviews 3.2 (2016), 48-54. Print.



APA (American Psychological Association) Style

HETAL PATEL, MUKESH GOHEL (2016) A REVIEW ON DEVELOPMENT OF MULTIFUNCTIONAL CO-PROCESSED EXCIPIENT. Journal of Critical Reviews, 3 (2), 48-54.