ISSN 2394-5125
 

Research Article 


THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar.

Abstract
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver.Objective: To understand the serum levels of thyroid hormones (fT3, fT4, TSH) and identify the related influencing factors of thyroid hormones levels in Ledipasvir/ Sofosbuvir (harvoni) drug users. Methods: From February to December 2019, a face-to-face questionnaire survey was conduct in 45 male and female before and after Harvoni drug users in GIT center in Baghdad province to collect their socio-demographic information. Then, venous blood sample was collect from each participant for the detection of thyroid hormones levels.Results:The mean of fT3, fT4, TSH for HCV patients before treatment [(4.9456 .75943) (5.69- 4.19)], [(15.9938 2.24645) (18.23- 13.75)], [(2.0761 1.20335) (3.27- 0.87)], respectively, where that after treatment [(6.2358 .62891) (6.85-5.61)], [(18.88421.56675) (20.44-17.32)], [(1.9151 .78820) (2.69-1.13)].Were significant differences (P<0.030), (P=0.027), (P=0.052) respectively.Conclusions: Free T4 and free T3 of TFT are more effected (decrease) by HCV because the above combined relationship, and response to Harvoni treatment.

Key words: Thyroid hormones, thyroid peroxidase enzyme, hepatitis C, Ledipasvir/ Sofosbuvir


 
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How to Cite this Article
Pubmed Style

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar. THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT. JCR. 2020; 7(17): 3188-3191. doi:10.31838/jcr.07.17.396


Web Style

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar. THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT. http://www.jcreview.com/?mno=24766 [Access: August 18, 2021]. doi:10.31838/jcr.07.17.396


AMA (American Medical Association) Style

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar. THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT. JCR. 2020; 7(17): 3188-3191. doi:10.31838/jcr.07.17.396



Vancouver/ICMJE Style

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar. THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT. JCR. (2020), [cited August 18, 2021]; 7(17): 3188-3191. doi:10.31838/jcr.07.17.396



Harvard Style

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar (2020) THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT. JCR, 7 (17), 3188-3191. doi:10.31838/jcr.07.17.396



Turabian Style

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar. 2020. THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT. Journal of Critical Reviews, 7 (17), 3188-3191. doi:10.31838/jcr.07.17.396



Chicago Style

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar. "THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT." Journal of Critical Reviews 7 (2020), 3188-3191. doi:10.31838/jcr.07.17.396



MLA (The Modern Language Association) Style

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar. "THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT." Journal of Critical Reviews 7.17 (2020), 3188-3191. Print. doi:10.31838/jcr.07.17.396



APA (American Psychological Association) Style

Raneem Rafea Mousa, Dr. EstabraqAR. Alwasiti, Dr. Bassim Ahmed Askar (2020) THYROID HORMONES AND THYROID PEROXIDASE ENZYMELEVEL IN PATIENTS WITH HEPATITIS C UNDER LEDIPASVIR/ SOFOSBUVIR (HARVONI) TREATMENT. Journal of Critical Reviews, 7 (17), 3188-3191. doi:10.31838/jcr.07.17.396