ISSN 2394-5125
 

Research Article 


VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA

Shady Mohammed El-Sebai, Hany Ahmed Samy, Ahmed Mohamed Shoukry, Reda Hasan Tabashy.

Abstract
For comparing contrast-enhanced subtractions magnetic resonance imaging (MRI) with
standard contrast-enhanced MRI in assessment treatments response followed transarterial
chemoembolization used drug eluting beads for hepatocellular carcinoma (HCC).
Material and Methods: Fifty patients (39 males and 11 females) having 62 HCC lesions underwent drug
eluting beads chemoembolization. Ages ranged from 44 to 71 years (mean age 53.1). All examinations
were performed using 1.5-T MRI (Achieva, Philips). Pre contrast sequences include T1WI, T2WI, inphase,
and out of phase gradient echo sequences. Post-contrast dynamic MRI sequence used was the
eTHRIVE method. Subtracted of un-enhanced T1-weight images of identically images on the contrastenhancement
sequence in early and late arterial phases.
Results: The first reader detected 40 well-ablated lesions by dynamic MRI. The second reader detected
residual activity in 4 lesions out of the 40 lesions (10%) via subtraction MRI. The second reader agreed
with the first reader in 36 lesions (90%).The first reader detected 22 residual lesions by dynamic MRI. The
second reader agreed with the first reader in 12 lesions (54.5%) where residual activity was confirmed. The
second reader disagreed with the first reader in 10 lesions (45.5%) where complete ablation was identified
via subtraction MRI.
Conclusion: Subtraction MRI improves the reader confidence level compared to standard contrastenhanced
MRI in treatments response assessing followed by drug eluting beads chemoembolization for
HCC.

Key words: Hepatocellular carcinoma Subtraction MRI Drug eluting beads chemoembolization


 
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How to Cite this Article
Pubmed Style

Shady Mohammed El-Sebai , Hany Ahmed Samy , Ahmed Mohamed Shoukry , Reda Hasan Tabashy. VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA. JCR. 2020; 7(7): 3955-3964. doi:10.31838/jcr.07.07.348


Web Style

Shady Mohammed El-Sebai , Hany Ahmed Samy , Ahmed Mohamed Shoukry , Reda Hasan Tabashy. VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA. http://www.jcreview.com/?mno=21538 [Access: April 18, 2021]. doi:10.31838/jcr.07.07.348


AMA (American Medical Association) Style

Shady Mohammed El-Sebai , Hany Ahmed Samy , Ahmed Mohamed Shoukry , Reda Hasan Tabashy. VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA. JCR. 2020; 7(7): 3955-3964. doi:10.31838/jcr.07.07.348



Vancouver/ICMJE Style

Shady Mohammed El-Sebai , Hany Ahmed Samy , Ahmed Mohamed Shoukry , Reda Hasan Tabashy. VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA. JCR. (2020), [cited April 18, 2021]; 7(7): 3955-3964. doi:10.31838/jcr.07.07.348



Harvard Style

Shady Mohammed El-Sebai , Hany Ahmed Samy , Ahmed Mohamed Shoukry , Reda Hasan Tabashy (2020) VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA. JCR, 7 (7), 3955-3964. doi:10.31838/jcr.07.07.348



Turabian Style

Shady Mohammed El-Sebai , Hany Ahmed Samy , Ahmed Mohamed Shoukry , Reda Hasan Tabashy. 2020. VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA. Journal of Critical Reviews, 7 (7), 3955-3964. doi:10.31838/jcr.07.07.348



Chicago Style

Shady Mohammed El-Sebai , Hany Ahmed Samy , Ahmed Mohamed Shoukry , Reda Hasan Tabashy. "VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA." Journal of Critical Reviews 7 (2020), 3955-3964. doi:10.31838/jcr.07.07.348



MLA (The Modern Language Association) Style

Shady Mohammed El-Sebai , Hany Ahmed Samy , Ahmed Mohamed Shoukry , Reda Hasan Tabashy. "VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA." Journal of Critical Reviews 7.7 (2020), 3955-3964. Print. doi:10.31838/jcr.07.07.348



APA (American Psychological Association) Style

Shady Mohammed El-Sebai , Hany Ahmed Samy , Ahmed Mohamed Shoukry , Reda Hasan Tabashy (2020) VALUE OF SUBTRACTION MRI IN ASSESSING TREATMENT RESPONSE AFTER DRUG ELUTING BEADS CHEMOEMBOLIZATION FOR HEPATOCELLULAR CARCINOMA. Journal of Critical Reviews, 7 (7), 3955-3964. doi:10.31838/jcr.07.07.348