ISSN 2394-5125
 

Research Article 


SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari.

Abstract
OSMF is a pre-cancerous condition of the oral cavity.1The oral precancerous condition as defined
by WHO is a generalized pathological state of the oral mucosa associated with a significantly increased risk of
cancer, which accords well with OSMF characteristics.2 OSCC is a common human malignant tumour with an
increasing incidence. It is a high-effect local disease in the oral cavity affecting over 300,000 people worldwide
annually.3 The coexistence of the oral squamous cell carcinoma (OSCC) and oral sub mucous fibrosis (OSMF)
is well documented in the literature and various studies have shown it to be 5% to 42%. The aim of the study
was to identify proteins that are differentially expressed in Oral Sub Mucous Fibrosis and Oral Squamous Cell
Carcinoma Patients.

Key words: Tissue samples of 9 patients (3 oral sub mucous fibrosis+ 3 oral squamous cell carcinoma + 3 healthy volunteers with habit of gutka chewing) were collected. The proteins in the samples were analysed using mass spectrometry to identify differentially expressed proteins.


 
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Pubmed Style

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari. SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY. JCR. 2020; 7(19): 6370-6378. doi:10.31838/jcr.07.19.733


Web Style

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari. SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY. http://www.jcreview.com/?mno=134929 [Access: August 17, 2021]. doi:10.31838/jcr.07.19.733


AMA (American Medical Association) Style

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari. SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY. JCR. 2020; 7(19): 6370-6378. doi:10.31838/jcr.07.19.733



Vancouver/ICMJE Style

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari. SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY. JCR. (2020), [cited August 17, 2021]; 7(19): 6370-6378. doi:10.31838/jcr.07.19.733



Harvard Style

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari (2020) SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY. JCR, 7 (19), 6370-6378. doi:10.31838/jcr.07.19.733



Turabian Style

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari. 2020. SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY. Journal of Critical Reviews, 7 (19), 6370-6378. doi:10.31838/jcr.07.19.733



Chicago Style

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari. "SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY." Journal of Critical Reviews 7 (2020), 6370-6378. doi:10.31838/jcr.07.19.733



MLA (The Modern Language Association) Style

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari. "SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY." Journal of Critical Reviews 7.19 (2020), 6370-6378. Print. doi:10.31838/jcr.07.19.733



APA (American Psychological Association) Style

Anand Sekhar, Sripathi Rao, Vinaykrishna Kolari (2020) SALIVARY PROTEIN EXPRESSION ANALYSIS IN ORAL SUBMUCOUS FIBROSIS & ORAL SQUAMOUS CELL CARCINOMA: A PROTEOMIC STUDY. Journal of Critical Reviews, 7 (19), 6370-6378. doi:10.31838/jcr.07.19.733