ISSN 2394-5125
 

Research Article 


GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ

Magda A. Ali, Abdulsada A. Rahi.

Abstract
Nanoparticles (NPs) play an important role in the diagnosis and treatment of diseases in consequence of their larger
surface areas in comparison to the bulk material. Among the variety of nanomaterials, metal nanoparticles (MNPs)
present unique physical, chemical and biological properties. The present study was evaluated the anti-Leishmania effect
of silver nanoparticles on Leishmania major based on investigation of their action on various cellular parameters of the
promastigote and amastigote forms of parasite.
Silver nanoparticles were synthesized using tannic acid (TA) as both reducing and stabilizer and monitored by UV–vis
absorption spectroscopy and scanning electron microscopy (SEM) images that showed the formation of spherical AgNPs
ranging from 5 to 24 nm diameter.
TA coating resulted in a red-shift and broadening of bands. In vitro assays of Leishmania major promastigotes showed
an increase of antileishmanial activity for AgNPs-TA. This screening can contribute to the development of new, green,
and fast produced drugs aiming at leishmaniasis treatment. Moreover these biologically synthesized nanoparticles were
found to be highly effective against different multi-drug resistant human pathogens.

Key words: green synthesis, leishmaniasis, metallic nanoparticles, tannic acid.


 
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Pubmed Style

Magda A. Ali, Abdulsada A. Rahi. GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ . JCR. 2020; 7(5): 2188-2191. doi:10.31838/jcr.07.05.374


Web Style

Magda A. Ali, Abdulsada A. Rahi. GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ . http://www.jcreview.com/?mno=130983 [Access: August 18, 2021]. doi:10.31838/jcr.07.05.374


AMA (American Medical Association) Style

Magda A. Ali, Abdulsada A. Rahi. GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ . JCR. 2020; 7(5): 2188-2191. doi:10.31838/jcr.07.05.374



Vancouver/ICMJE Style

Magda A. Ali, Abdulsada A. Rahi. GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ . JCR. (2020), [cited August 18, 2021]; 7(5): 2188-2191. doi:10.31838/jcr.07.05.374



Harvard Style

Magda A. Ali, Abdulsada A. Rahi (2020) GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ . JCR, 7 (5), 2188-2191. doi:10.31838/jcr.07.05.374



Turabian Style

Magda A. Ali, Abdulsada A. Rahi. 2020. GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ . Journal of Critical Reviews, 7 (5), 2188-2191. doi:10.31838/jcr.07.05.374



Chicago Style

Magda A. Ali, Abdulsada A. Rahi. "GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ ." Journal of Critical Reviews 7 (2020), 2188-2191. doi:10.31838/jcr.07.05.374



MLA (The Modern Language Association) Style

Magda A. Ali, Abdulsada A. Rahi. "GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ ." Journal of Critical Reviews 7.5 (2020), 2188-2191. Print. doi:10.31838/jcr.07.05.374



APA (American Psychological Association) Style

Magda A. Ali, Abdulsada A. Rahi (2020) GREEN SYNTHESIS AND TREATMENT OF SILVER NANOPARTICLES FROM LEISHMANIA MAJOR IN IRAQ . Journal of Critical Reviews, 7 (5), 2188-2191. doi:10.31838/jcr.07.05.374