ISSN 2394-5125
 

Research Article 


PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN.

Abstract
Predictive analytics assist and improve healthcare management of patients as follow-ups to percutaneous coronary intervention (PCI) procedure. This research aimed to construct, validate, and measure performance of three predictive models in predicting major adverse cardiac events (MACE) within one year after PCI. This study utilized data of 10511 patients who underwent PCI at the National Heart Institute (IJN) between 2008 and 2012. The data mainly consisted of information on patientís demographic, health status before and during the PCI procedure, and MACE outcome within one year after the procedure. The data was split into development and validation datasets. After variable selection process, predictive models based on logistic regression, artificial neural network (ANN), and decision tree were developed using the development data set. Each model then validated using the validation dataset. Performance of the models were measured using Matthews correlation coefficient (MCC). MACE occurred amongst 12.9% patients during 1-year follow-up. Fifteen predictors were identified to significantly associated with 1-year MACE. ANN model gave the best performance, followed by logistic regression and decision tree.ANN is a reliable model to predict MACE case after PCI procedure. The findings enlighten clinicians and patients to plan better management after PCI.

Key words: Percutaneous coronary intervention, Major adverse cardiac event, Predictive model


 
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Pubmed Style

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN. PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.. JCR. 2020; 7(10): 2155-2160. doi:10.31838/jcr.07.10.372


Web Style

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN. PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.. http://www.jcreview.com/?mno=120806 [Access: August 18, 2021]. doi:10.31838/jcr.07.10.372


AMA (American Medical Association) Style

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN. PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.. JCR. 2020; 7(10): 2155-2160. doi:10.31838/jcr.07.10.372



Vancouver/ICMJE Style

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN. PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.. JCR. (2020), [cited August 18, 2021]; 7(10): 2155-2160. doi:10.31838/jcr.07.10.372



Harvard Style

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN (2020) PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.. JCR, 7 (10), 2155-2160. doi:10.31838/jcr.07.10.372



Turabian Style

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN. 2020. PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.. Journal of Critical Reviews, 7 (10), 2155-2160. doi:10.31838/jcr.07.10.372



Chicago Style

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN. "PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.." Journal of Critical Reviews 7 (2020), 2155-2160. doi:10.31838/jcr.07.10.372



MLA (The Modern Language Association) Style

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN. "PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.." Journal of Critical Reviews 7.10 (2020), 2155-2160. Print. doi:10.31838/jcr.07.10.372



APA (American Psychological Association) Style

NORHAFIZAH AB MANAN, AHMAD KHAIRUDDIN, BASIR ABIDIN (2020) PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.. Journal of Critical Reviews, 7 (10), 2155-2160. doi:10.31838/jcr.07.10.372