ISSN 2394-5125
 

Research Article 


MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif.

Abstract
Platinum analogs includes cisplatin, oxaliplatin and carboplatin. Cisplatin is a chemotherapeutic drug with excellent success in the management of human malignancies. Molecular mechanism of action related to its capacity to crosslink of DNA purine bases; also by interfere with DNA repair, leading to DNA break, and consequently lead to apoptosis in cancer cells. Cisplatin also found to have immunomodulatory properties besides its cytotoxic effect.

Key words: Cisplatin, Cancer, Molecular and Immunomodulatory Effects, Genes Repair.


 
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Pubmed Style

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif. MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE. JCR. 2020; 7(9): 81-83. doi:10.31838/jcr.07.09.14


Web Style

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif. MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE. http://www.jcreview.com/?mno=112325 [Access: May 30, 2021]. doi:10.31838/jcr.07.09.14


AMA (American Medical Association) Style

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif. MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE. JCR. 2020; 7(9): 81-83. doi:10.31838/jcr.07.09.14



Vancouver/ICMJE Style

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif. MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE. JCR. (2020), [cited May 30, 2021]; 7(9): 81-83. doi:10.31838/jcr.07.09.14



Harvard Style

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif (2020) MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE. JCR, 7 (9), 81-83. doi:10.31838/jcr.07.09.14



Turabian Style

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif. 2020. MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE. Journal of Critical Reviews, 7 (9), 81-83. doi:10.31838/jcr.07.09.14



Chicago Style

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif. "MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE." Journal of Critical Reviews 7 (2020), 81-83. doi:10.31838/jcr.07.09.14



MLA (The Modern Language Association) Style

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif. "MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE." Journal of Critical Reviews 7.9 (2020), 81-83. Print. doi:10.31838/jcr.07.09.14



APA (American Psychological Association) Style

Dalia Abdalkader Shakur, Suhad Faisal Hatem Al-Mugdadi, Inam S. Arif (2020) MOLECULAR MECHANISMS AND IMMUNOMODULATORY EFFECTS OF PLATINUM ANALOGS ON SOME GENES AND AS ANTICANCER DRUGS: REVIEW ARTICLE. Journal of Critical Reviews, 7 (9), 81-83. doi:10.31838/jcr.07.09.14