ISSN 2394-5125
 

Research Article 


EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS

K.Sangeetha, Dr.S.Selvakumar , Merina Paul Das.

Abstract
The emergence of resistant strains necessitates the search for newer antibitotics from the existing sources.As the non
antibiotics such as antihistamines, psychotropics, antihypertensives, anaesthetics, anti- inflammatory drugs were
found to possess antibacterial activity. Thus the study was carried out with an objective to analyze the antibacterial
activity of anticonvulsant drugs. Antibacterial activity of the anticonvulsant drugs namely Carbamazepine,
Primedase, Lobazam, Lonazep,Gabapentine,Valproic acid,Lametec ,Valparin alka were estimated by both the Agar
well dilution and Minimum inhibitory concentration method .Also the bactericidal and bacteriostatic property of the
effective drugs were determined by estimating the number colony forming units of the microorganisms tested
.Gabapentine and carbamazepine were ineffective to the bacterial isolates. Valproic acid was highly effective to
Staphylococcus aureus and Proteus vulgaris at the concentration of 100 μg/ml whereas inhibited the other tested
organisms greater than 200 μg/ml .Hence of all the tested anticonvulsant drugs Valproic acid was the only drug
found to be effective against the tested bacteria by in vitro analysis.

Key words: Staphylococcus aureus and Proteus vulgaris


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by K.Sangeetha
Articles by Dr.S.Selvakumar
Articles by Merina Paul Das
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

K.Sangeetha , Dr.S.Selvakumar , Merina Paul Das. EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS. JCR. 2020; 7(7): 2003-2008. doi:10.31838/jcr.07.07.317


Web Style

K.Sangeetha , Dr.S.Selvakumar , Merina Paul Das. EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS. http://www.jcreview.com/?mno=111759 [Access: May 31, 2021]. doi:10.31838/jcr.07.07.317


AMA (American Medical Association) Style

K.Sangeetha , Dr.S.Selvakumar , Merina Paul Das. EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS. JCR. 2020; 7(7): 2003-2008. doi:10.31838/jcr.07.07.317



Vancouver/ICMJE Style

K.Sangeetha , Dr.S.Selvakumar , Merina Paul Das. EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS. JCR. (2020), [cited May 31, 2021]; 7(7): 2003-2008. doi:10.31838/jcr.07.07.317



Harvard Style

K.Sangeetha , Dr.S.Selvakumar , Merina Paul Das (2020) EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS. JCR, 7 (7), 2003-2008. doi:10.31838/jcr.07.07.317



Turabian Style

K.Sangeetha , Dr.S.Selvakumar , Merina Paul Das. 2020. EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS. Journal of Critical Reviews, 7 (7), 2003-2008. doi:10.31838/jcr.07.07.317



Chicago Style

K.Sangeetha , Dr.S.Selvakumar , Merina Paul Das. "EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS." Journal of Critical Reviews 7 (2020), 2003-2008. doi:10.31838/jcr.07.07.317



MLA (The Modern Language Association) Style

K.Sangeetha , Dr.S.Selvakumar , Merina Paul Das. "EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS." Journal of Critical Reviews 7.7 (2020), 2003-2008. Print. doi:10.31838/jcr.07.07.317



APA (American Psychological Association) Style

K.Sangeetha , Dr.S.Selvakumar , Merina Paul Das (2020) EVALUATION OF IN VITRO ANTIBACTERIAL ACTIVITY OF ANTICONVULSANT DRUGS. Journal of Critical Reviews, 7 (7), 2003-2008. doi:10.31838/jcr.07.07.317