ISSN 2394-5125
 

Research Article 


ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS

Hamed Amirifard, Mohammad Sedaghat, Alireza khosravi, Payam Naghash, Shima Mansornia, Zahra Nezamdoust.

Abstract
Introduction: Multiple Sclerosis (MS) is a neurological disorder in which demyelination and axonal degeneration lead to progressive disability. The main objective of the present study was to investigate the relationship between the thicknesses of the retinal nerve fiber layer (RNFL) with optic nerve diameter in MRI of patients with multiple sclerosis,with and without optic neuritis.
Material & methods: Five Multiple Sclerosis patients were evaluated in this cross-sectional study. The patients without optic neuritis were also randomly selected and matched for age and sex with the affected group. Afterward, in order to measure the diameter and head OCT of optic nerve, optic nerve MRI was done to determine the RNFL thickness in these patients. Statistical analysis was done by utilizing the SPSS 22 software.
Results: The mean RNFL thickness of patients with and without optic neuritis were 85.5 10.7 μm and 94.3 11.6 μm, respectively. The mean values for optic nerve diameter of patients with and without optic neuritis were 4.1 0.6 mm and 3.2 5.5 mm, respectively. In patients with MS and optic neuritis, the RNFL thickness was significantly lower than MS patients without optic neuritis. The diameter of optic nerve was significantly higher in patients with optic neuritis.
Conclusion: There is a negative and significant relationship between optic nerve diameter and RNFL thickness only in patients with MS and optic neuritis.

Key words: Multiple Sclerosis, optic neuritis, RNFL thickness, optic nerve diameter.


 
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How to Cite this Article
Pubmed Style

Hamed Amirifard , Mohammad Sedaghat , Alireza khosravi , Payam Naghash , Shima Mansornia , Zahra Nezamdoust. ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS. JCR. 2020; 7(7): 1104-1107. doi:10.31838/jcr.07.07.203


Web Style

Hamed Amirifard , Mohammad Sedaghat , Alireza khosravi , Payam Naghash , Shima Mansornia , Zahra Nezamdoust. ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS. http://www.jcreview.com/?mno=111746 [Access: May 31, 2021]. doi:10.31838/jcr.07.07.203


AMA (American Medical Association) Style

Hamed Amirifard , Mohammad Sedaghat , Alireza khosravi , Payam Naghash , Shima Mansornia , Zahra Nezamdoust. ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS. JCR. 2020; 7(7): 1104-1107. doi:10.31838/jcr.07.07.203



Vancouver/ICMJE Style

Hamed Amirifard , Mohammad Sedaghat , Alireza khosravi , Payam Naghash , Shima Mansornia , Zahra Nezamdoust. ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS. JCR. (2020), [cited May 31, 2021]; 7(7): 1104-1107. doi:10.31838/jcr.07.07.203



Harvard Style

Hamed Amirifard , Mohammad Sedaghat , Alireza khosravi , Payam Naghash , Shima Mansornia , Zahra Nezamdoust (2020) ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS. JCR, 7 (7), 1104-1107. doi:10.31838/jcr.07.07.203



Turabian Style

Hamed Amirifard , Mohammad Sedaghat , Alireza khosravi , Payam Naghash , Shima Mansornia , Zahra Nezamdoust. 2020. ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS. Journal of Critical Reviews, 7 (7), 1104-1107. doi:10.31838/jcr.07.07.203



Chicago Style

Hamed Amirifard , Mohammad Sedaghat , Alireza khosravi , Payam Naghash , Shima Mansornia , Zahra Nezamdoust. "ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS." Journal of Critical Reviews 7 (2020), 1104-1107. doi:10.31838/jcr.07.07.203



MLA (The Modern Language Association) Style

Hamed Amirifard , Mohammad Sedaghat , Alireza khosravi , Payam Naghash , Shima Mansornia , Zahra Nezamdoust. "ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS." Journal of Critical Reviews 7.7 (2020), 1104-1107. Print. doi:10.31838/jcr.07.07.203



APA (American Psychological Association) Style

Hamed Amirifard , Mohammad Sedaghat , Alireza khosravi , Payam Naghash , Shima Mansornia , Zahra Nezamdoust (2020) ASSOCIATION BETWEEN THICKNESS OF RETINAL NERVE FIBER LAYER AND OPTIC NERVE DIAMETERS IN WITH PATIENTS WITH MULTIPLE SCLEROSIS. Journal of Critical Reviews, 7 (7), 1104-1107. doi:10.31838/jcr.07.07.203