ISSN 2394-5125
 

Research Article 


ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION

Mirzaeva Dilfuza, Sadjalilova Dilnoza.

Abstract
A molecular genetics study was conducted in 143 pregnant women after IVF. The polymorphism
of thrombophilic blood genes was studied during the development of miscarriage after an IVF procedure. Studies
have shown the relationship between the presence of miscarriage during IVF with genetic disorders of the
hemostatic system. Genetic mutations of the hemostatic system in women with IVF, whose pregnancy ended in
miscarriage, were detected in 61.6%, and among women with a physiological pregnancy during IVF, in 31.6%.
The risk of miscarriage in patients with IVF increased more than 6 times higher in the presence of combined
thrombophilic mutations than in carriers of individual gene alleles. In this regard, the early detection and
detection of mutations in the genes of the blood coagulation system and pathogenetic prophylaxis in order to
normalize hemostasiological parameters in pregnant women with IVF will reduce the rate of miscarriage.

Key words: in vitro fertilization, thrombophilia genes, gene polymorphism, miscarriage


 
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Pubmed Style

Mirzaeva Dilfuza, Sadjalilova Dilnoza. ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION. JCR. 2020; 7(9): 2627-2629. doi:10.31838/jcr.07.09.424


Web Style

Mirzaeva Dilfuza, Sadjalilova Dilnoza. ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION. http://www.jcreview.com/?mno=108929 [Access: May 30, 2021]. doi:10.31838/jcr.07.09.424


AMA (American Medical Association) Style

Mirzaeva Dilfuza, Sadjalilova Dilnoza. ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION. JCR. 2020; 7(9): 2627-2629. doi:10.31838/jcr.07.09.424



Vancouver/ICMJE Style

Mirzaeva Dilfuza, Sadjalilova Dilnoza. ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION. JCR. (2020), [cited May 30, 2021]; 7(9): 2627-2629. doi:10.31838/jcr.07.09.424



Harvard Style

Mirzaeva Dilfuza, Sadjalilova Dilnoza (2020) ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION. JCR, 7 (9), 2627-2629. doi:10.31838/jcr.07.09.424



Turabian Style

Mirzaeva Dilfuza, Sadjalilova Dilnoza. 2020. ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION. Journal of Critical Reviews, 7 (9), 2627-2629. doi:10.31838/jcr.07.09.424



Chicago Style

Mirzaeva Dilfuza, Sadjalilova Dilnoza. "ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION." Journal of Critical Reviews 7 (2020), 2627-2629. doi:10.31838/jcr.07.09.424



MLA (The Modern Language Association) Style

Mirzaeva Dilfuza, Sadjalilova Dilnoza. "ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION." Journal of Critical Reviews 7.9 (2020), 2627-2629. Print. doi:10.31838/jcr.07.09.424



APA (American Psychological Association) Style

Mirzaeva Dilfuza, Sadjalilova Dilnoza (2020) ROLE OF GENETIC STUDIES OF THE HAEMOSTATIC SYSTEM IN THE EFFECTIVENESS OF IN VITRO FERTILIZATION. Journal of Critical Reviews, 7 (9), 2627-2629. doi:10.31838/jcr.07.09.424