ISSN 2394-5125
 

Research Article 


ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS

Sameer Zope, Apurva Ashok Pisal.

Abstract
Introduction The oral cavity is a mirror of the body and reflects the general health and well-being of an individual. Humans have been afflicted by major oral diseases such as periodontal diseases and dental caries since time immemorial.
Methods The prospective study design was explained to the subjects prior to their enrollment in the study. They were evaluated before and after treatment for clinical and biochemical parameters. The subjects for the study were selected from the patients attending the outpatient Department after due approval of the Ethical committee. The study comprised of 50 subjects who fulfilled the inclusion criteria. The subjects included both sexes in the age group of 18-45 years.
Results The group tested consisted of 28 males and 22 females, which consisted of 56% of males and 44% of female subjects. The mean age of the group was 37.6 ± 5.7 years. The mean HCY value was 20.7± 3.4 µmol/L while the mean post treatment HCY values were14.7± 2.2 µmol/L. The baseline Gingival Index was 2.0± 0.27 which indicates severe gingival inflammation. Following treatment the Gingival Index was 1.1± 0.22 which indicates moderate gingivitis. Baseline simplified oral hygiene index was 2.6 ± 0.5 which indicated poor oral hygiene while after treatment it was 1.6 ± 0.9 which indicate fair oral hygiene. There was an improvement of 1.0 ± 0.5 with a percentage change of 61.5%. There was no correlation found between any of the HYC, OHIS and GI (p>0.05) for pre scores as the correlation values found were, HYC and OHIS: r= -0.10, HYC and GI:r= 0.12, OHIS and GI: r= -0.15. Similarly when the correlation was compared between HYC, OHIS and GI (p>0.05) for post scores there was no correlation as the values found were, HYC and OHIS: r= -0.02, HYC and GI: r= 0.24, OHIS and GI: r= -0.05. There was no statistical significant difference found between Hcy levels of males and females, both pre operatively and post operatively. There was no correlation found between HYC and age.
Conclusion The elevated levels of plasma homocysteine in chronic periodontitis patients could be a marker for systemic inflammation. Moreover periodontal treatment can be used to augment conventional homocysteine lowering therapies.

Key words: Periodontal Therapy, Plasma Homocysteine, Patients, Periodontitis.


 
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Pubmed Style

Sameer Zope, Apurva Ashok Pisal. ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS. JCR. 2020; 7(7): 665-668. doi:10.31838/jcr.07.07.121


Web Style

Sameer Zope, Apurva Ashok Pisal. ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS. http://www.jcreview.com/?mno=107671 [Access: April 17, 2021]. doi:10.31838/jcr.07.07.121


AMA (American Medical Association) Style

Sameer Zope, Apurva Ashok Pisal. ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS. JCR. 2020; 7(7): 665-668. doi:10.31838/jcr.07.07.121



Vancouver/ICMJE Style

Sameer Zope, Apurva Ashok Pisal. ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS. JCR. (2020), [cited April 17, 2021]; 7(7): 665-668. doi:10.31838/jcr.07.07.121



Harvard Style

Sameer Zope, Apurva Ashok Pisal (2020) ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS. JCR, 7 (7), 665-668. doi:10.31838/jcr.07.07.121



Turabian Style

Sameer Zope, Apurva Ashok Pisal. 2020. ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS. Journal of Critical Reviews, 7 (7), 665-668. doi:10.31838/jcr.07.07.121



Chicago Style

Sameer Zope, Apurva Ashok Pisal. "ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS." Journal of Critical Reviews 7 (2020), 665-668. doi:10.31838/jcr.07.07.121



MLA (The Modern Language Association) Style

Sameer Zope, Apurva Ashok Pisal. "ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS." Journal of Critical Reviews 7.7 (2020), 665-668. Print. doi:10.31838/jcr.07.07.121



APA (American Psychological Association) Style

Sameer Zope, Apurva Ashok Pisal (2020) ASSESSMENT OF NON- SURGICAL PERIODONTAL THERAPY ON PLASMA HOMOCYSTEINE LEVELS IN CHRONIC PERIODONTITIS. Journal of Critical Reviews, 7 (7), 665-668. doi:10.31838/jcr.07.07.121