ISSN 2394-5125
 

Research Article 


Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?

Farva Abbas1, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima3,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool4, Umar Sajid Kayani, Bushra Gul.

Abstract
Pakistan has diverse genealogical foundation with rushes of movement from
neighboringareas.TherisingtrendofbreastcancerisonsuchafastpaceinPakistan, that it is now important to check the
contributing causes. Investigation about BRCA1/2 is necessary to augment the cancer genetics. Especially the national
level statistical data about hereditary mutations in different ethnicities in Pakistan is the need of an hour. Knowledge
about the information regarding prevalence, underscores the formulation of a hereditary and non-hereditary BRCA1/2
mutational database in Pakistan. This review article is delved to summarize the past studies and investigations about
BRCA1/2 in the country. Function, structure, different variants in ethnic groups and involvement of the BRCA1/2
genes is assessed. Initiatives taken by the government of Pakistan for the surveillance of breast cancer in Pakistan are
debated. Questions like what are the most common BRCA1/2 mutation in Pakistani population is also answered by
summing up the available data and studies.

Key words: BRCA1/2, Breast cancer, Pakistan, genealogical, hereditary


 
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How to Cite this Article
Pubmed Style

Farva Abbas, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool, Umar Sajid Kayani, Bushra Gul. Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?. JCR. 2021; 8(3): 18-33. doi:10.31838/jcr.08.03.03


Web Style

Farva Abbas, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool, Umar Sajid Kayani, Bushra Gul. Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?. http://www.jcreview.com/?mno=101953 [Access: August 16, 2021]. doi:10.31838/jcr.08.03.03


AMA (American Medical Association) Style

Farva Abbas, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool, Umar Sajid Kayani, Bushra Gul. Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?. JCR. 2021; 8(3): 18-33. doi:10.31838/jcr.08.03.03



Vancouver/ICMJE Style

Farva Abbas, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool, Umar Sajid Kayani, Bushra Gul. Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?. JCR. (2021), [cited August 16, 2021]; 8(3): 18-33. doi:10.31838/jcr.08.03.03



Harvard Style

Farva Abbas, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool, Umar Sajid Kayani, Bushra Gul (2021) Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?. JCR, 8 (3), 18-33. doi:10.31838/jcr.08.03.03



Turabian Style

Farva Abbas, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool, Umar Sajid Kayani, Bushra Gul. 2021. Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?. Journal of Critical Reviews, 8 (3), 18-33. doi:10.31838/jcr.08.03.03



Chicago Style

Farva Abbas, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool, Umar Sajid Kayani, Bushra Gul. "Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?." Journal of Critical Reviews 8 (2021), 18-33. doi:10.31838/jcr.08.03.03



MLA (The Modern Language Association) Style

Farva Abbas, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool, Umar Sajid Kayani, Bushra Gul. "Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?." Journal of Critical Reviews 8.3 (2021), 18-33. Print. doi:10.31838/jcr.08.03.03



APA (American Psychological Association) Style

Farva Abbas, Tayyaba Shan, Syed Waqas Hassan, Irum Fatima,Faiza Sattar, Kiran Jackson, Farhan Elahi Hashmi,Mariam Batool, Umar Sajid Kayani, Bushra Gul (2021) Status of BRCA1/2 in Breast Cancer Patients; where Pakistan stands?. Journal of Critical Reviews, 8 (3), 18-33. doi:10.31838/jcr.08.03.03