Abstract

Albendazole was found to be considerably more active than other benzimidazoles. This was because it was metabolized to albendazole sulphoxide which was also an active anthelminthic, while almost all other benzimidazoles were metabolized to inactive compounds. Preliminary batches of albendazole jelly were prepared using physical appearance, stickiness and grittiness using gum acacia, Tragacanth, sodium alginate and gelatin as viscosity agent, glycerin as a humectant protector, propyl paraben and methyl paraben as a preservatives, sucrose as a sweetening agent and citric acid as a antioxidant. From the evaluation study, it was observed that, as the concentration of polymer was increased, stickiness of jelly was decreased and as the concentration of polymer was decreased, stickiness and grittiness of jelly was increased

Description