Abstract
Simmonds disease is otherwise known as hypopituitarism. Causes of simmonds disease include tumor relate d, trauma, radiation therapy, auto immune disorders, symptoms of Simmonds disease are amenorrhea, galactorrhea, fatigue as well as weakness, weight gain, cold sensitivity, dry skin as well as hair, hypoglycemia, infertility. D iagnosis of simmonds disease include patients background information, past medical history, nutritional status assessments. Differential diagnosis is related to hypo pituitarism, thyroid disorders, growth hormone deficiency, adren o cortical tumors, central diabetes insipidus. Treatment of simmonds diseaseis linked to hormone replacemrnt therapy, corticosteroid replacement, growth hormone replacement, management of diabetes insipidus and surgery. It is co ncluded that early disgnosis and right time treatment are crucial for managing this disorder in an effective manner.