ISSN 2394-5125
 

Review Article 


AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh.

Abstract
Objectives: To explore the effect of levodopa against cortical functions, fatigue severity and health-related quality of life on patients with Parkinsonís disease.
Methods: A clinical control trial was conducted at primary healthcare centers at Gia Lai province from September 2018 to November 2019. Fifty idiopathic Parkinsonian patients and fifty control individuals were enrolled. The measurements were cortical function assessment (CFA), fatigue severity scale (FSS), and 39-item Parkinsonís disease questionnaire (PDQ-39). Descriptive analysis was used to perform the difference before and after treatment with L-Dopa.
Results: I-PD affected patients also had signs of cortical functioning deficits, severe fatigue experiences and deteriorated health-related quality than healthy individuals. The medication of L-Dopa significantly improved the life quality and reduced the fatigue severity in the timeframe of three months. Severe fatigue and deteriorated health also had an association with higher cortical functioning deficits. Cortical functioning also predicted about the fatigue severity and health-related quality.
Conclusion: The findings specifically suggest that L-Dopa treatment is very successful for cortical dysfunctions, severe fatigue and health-related quality of life among the patients of I-PD. Cortical functioning significantly indicates life quality and fatigue factor in the patients of I-PD.

Key words: Cognition, Cortical, Chronic Fatigue, Health-Related Quality of Life, Levodopa, Parkinson.


 
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How to Cite this Article
Pubmed Style

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh. AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS. JCR. 2020; 7(4): 78-81. doi:10.31838/jcr.07.04.16


Web Style

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh. AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS. http://www.jcreview.com/?mno=93412 [Access: March 18, 2020]. doi:10.31838/jcr.07.04.16


AMA (American Medical Association) Style

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh. AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS. JCR. 2020; 7(4): 78-81. doi:10.31838/jcr.07.04.16



Vancouver/ICMJE Style

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh. AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS. JCR. (2020), [cited March 18, 2020]; 7(4): 78-81. doi:10.31838/jcr.07.04.16



Harvard Style

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh (2020) AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS. JCR, 7 (4), 78-81. doi:10.31838/jcr.07.04.16



Turabian Style

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh. 2020. AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS. Journal of Critical Reviews, 7 (4), 78-81. doi:10.31838/jcr.07.04.16



Chicago Style

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh. "AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS." Journal of Critical Reviews 7 (2020), 78-81. doi:10.31838/jcr.07.04.16



MLA (The Modern Language Association) Style

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh. "AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS." Journal of Critical Reviews 7.4 (2020), 78-81. Print. doi:10.31838/jcr.07.04.16



APA (American Psychological Association) Style

Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Quang Vinh Tran, Khang Kim Huynh (2020) AN ASSESSMENT OF THE EFFECTIVENESS OF THREE-MONTH MANAGEMENT OF IDIOPATHIC PARKINSONíS DISEASE (I-PD) WITH LEVODOPA (L-DOPA) TO TREAT FATIGUE SEVERITY, HRQOL AND CORTICAL DYSFUNCTIONS. Journal of Critical Reviews, 7 (4), 78-81. doi:10.31838/jcr.07.04.16