ISSN 2394-5125
 

Review Article 


Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital

Mastaneh Afshar, Sara Fathizadeh, Mina Boustanshenas, Somayeh Soleymanzadeh Moghadam, Maryam Roham.

Abstract
Background: Acinetobacter baumannii, as a nosocomial opportunistic pathogen, is resistant to a wide range of antibiotics and is responsible for numerous infections including bacteria, pneumonia, meningitis, urinary tract infections and wounds. The aim of this study was to determine frequency of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients
Materials & methods:A total of 108 A. baumannii strains were collected from burn patients admitted to Motahari hospital, Iran. Antimicrobial susceptibility testing was performed according to the Kirby Bauer disk diffusion method. DNA extraction and Typing of strains was performed by PCR amplification of repetitive extragenic palindromic elements (REP-PCR).
Results: Our results showed that 98 strains were identified as A. baumannii by phenotypic tests. Also, 96 of 98 strains were PCR positive for blaOXA-51-like genes. Based on Antimicrobial susceptibility test 84 isolates (87.5%) were colistin sensitive, and 12 strains (12.5%) were resistant to colistin.
Conclusion: Our results showed that the incidence of A. baumannii strains is high in patients and blaOXA-51-like was the most prevalent gene among the burn clinical isolates of A. baumannii. Also, more than 85% of the isolates were resistant to most antibiotics.

Key words: Acinetobacter baumannii, blaOXA-51, MDR, infection, nosocomial.


 
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How to Cite this Article
Pubmed Style

Mastaneh Afshar , Sara Fathizadeh , Mina Boustanshenas , Somayeh Soleymanzadeh Moghadam , Maryam Roham. Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital . JCR. 2020; 7(1): 91-95. doi:10.22159/jcr.07.01.18


Web Style

Mastaneh Afshar , Sara Fathizadeh , Mina Boustanshenas , Somayeh Soleymanzadeh Moghadam , Maryam Roham. Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital . http://www.jcreview.com/?mno=302645147 [Access: September 15, 2020]. doi:10.22159/jcr.07.01.18


AMA (American Medical Association) Style

Mastaneh Afshar , Sara Fathizadeh , Mina Boustanshenas , Somayeh Soleymanzadeh Moghadam , Maryam Roham. Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital . JCR. 2020; 7(1): 91-95. doi:10.22159/jcr.07.01.18



Vancouver/ICMJE Style

Mastaneh Afshar , Sara Fathizadeh , Mina Boustanshenas , Somayeh Soleymanzadeh Moghadam , Maryam Roham. Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital . JCR. (2020), [cited September 15, 2020]; 7(1): 91-95. doi:10.22159/jcr.07.01.18



Harvard Style

Mastaneh Afshar , Sara Fathizadeh , Mina Boustanshenas , Somayeh Soleymanzadeh Moghadam , Maryam Roham (2020) Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital . JCR, 7 (1), 91-95. doi:10.22159/jcr.07.01.18



Turabian Style

Mastaneh Afshar , Sara Fathizadeh , Mina Boustanshenas , Somayeh Soleymanzadeh Moghadam , Maryam Roham. 2020. Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital . Journal of Critical Reviews, 7 (1), 91-95. doi:10.22159/jcr.07.01.18



Chicago Style

Mastaneh Afshar , Sara Fathizadeh , Mina Boustanshenas , Somayeh Soleymanzadeh Moghadam , Maryam Roham. "Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital ." Journal of Critical Reviews 7 (2020), 91-95. doi:10.22159/jcr.07.01.18



MLA (The Modern Language Association) Style

Mastaneh Afshar , Sara Fathizadeh , Mina Boustanshenas , Somayeh Soleymanzadeh Moghadam , Maryam Roham. "Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital ." Journal of Critical Reviews 7.1 (2020), 91-95. Print. doi:10.22159/jcr.07.01.18



APA (American Psychological Association) Style

Mastaneh Afshar , Sara Fathizadeh , Mina Boustanshenas , Somayeh Soleymanzadeh Moghadam , Maryam Roham (2020) Evaluation of molecular epidemiology and antibiotic susceptibility of Acinetobacter baumanii, in burned patients of Motahari hospital . Journal of Critical Reviews, 7 (1), 91-95. doi:10.22159/jcr.07.01.18