ISSN 2394-5125
 

Review Article 


A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION

MANASVI BOMMAREDDY, SHRIPAD HEBBAR.

Abstract
One of the major problems in obstetrics and neonatology till today is the occurrence of preterm births in spite of best possible antenatal care. Many
preterm labour are due to PPROM (Prelabour Preterm Rupture of Membranes) where infection plays a major role. The neonatal morbidity and
mortality is directly related to maternal infection and early-onset neonatal sepsis. Laboratory evaluation of various inflammatory markers such as
TLC (total leucocyte count), ESR (Erythrocyte Sedimentation Rate), CRP (C-Reactive Protein) predict events such as maternal chorioamnionitis,
neonatal sepsis with reasonable accuracy and hence are valuable tools in high dependency obstetric (HDU) and neonatal intensive care units
(NICU). The following treatise mainly focusses on aetiopathogenesis, clinical features, haematological and biochemical parameters of maternal
PPROM and neonatal sepsis. Understanding these factors will definitely prevent adverse maternal outcomes such as postpartum infections and
puerperal sepsis and perinatal events such as stillbirth due to intrauterine foetal infection, preterm birth, neonatal sepsis, long term sequele of
chronic lung disease and brain injury leading to cerebral palsy and other neurodevelopmental disabilities.

Key words: PPROM, EONI, Chorioamnionitis, C Reactive Protein, Neonatal sepsis


 
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Pubmed Style

BOMMAREDDY M, HEBBAR S. A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION. JCR. 2019; 6(3): 7-13. doi:10.22159/jcr.2019v6i3.31792


Web Style

BOMMAREDDY M, HEBBAR S. A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION. http://www.jcreview.com/?mno=302644735 [Access: March 08, 2020]. doi:10.22159/jcr.2019v6i3.31792


AMA (American Medical Association) Style

BOMMAREDDY M, HEBBAR S. A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION. JCR. 2019; 6(3): 7-13. doi:10.22159/jcr.2019v6i3.31792



Vancouver/ICMJE Style

BOMMAREDDY M, HEBBAR S. A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION. JCR. (2019), [cited March 08, 2020]; 6(3): 7-13. doi:10.22159/jcr.2019v6i3.31792



Harvard Style

BOMMAREDDY, M. & HEBBAR, . S. (2019) A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION. JCR, 6 (3), 7-13. doi:10.22159/jcr.2019v6i3.31792



Turabian Style

BOMMAREDDY, MANASVI, and SHRIPAD HEBBAR. 2019. A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION. Journal of Critical Reviews, 6 (3), 7-13. doi:10.22159/jcr.2019v6i3.31792



Chicago Style

BOMMAREDDY, MANASVI, and SHRIPAD HEBBAR. "A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION." Journal of Critical Reviews 6 (2019), 7-13. doi:10.22159/jcr.2019v6i3.31792



MLA (The Modern Language Association) Style

BOMMAREDDY, MANASVI, and SHRIPAD HEBBAR. "A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION." Journal of Critical Reviews 6.3 (2019), 7-13. Print. doi:10.22159/jcr.2019v6i3.31792



APA (American Psychological Association) Style

BOMMAREDDY, M. & HEBBAR, . S. (2019) A REVIEW ON PPROM (PRETERM PRELABOUR RUPTURE OF MEMBRANES) AND EARLY ONSET NEONATAL SEPSIS AND ROLE OF INFLAMMATORY MARKERS IN DIAGNOSIS OF MATERNAL AND NEONATAL INFECTION. Journal of Critical Reviews, 6 (3), 7-13. doi:10.22159/jcr.2019v6i3.31792